Neopentyl glycol (NPG, IUPAC name 2,2-dimethyl-1,3-propanediol) is an important industrial intermediate used in the synthesis of polyesters, especially resins for airplane or boat manufacturing. The neopentyl structure provides excellent resistance to light, heat, and hydrolysis. NPG is also being used in a variety of formulations in varnish coatings, synthetic lubricants, and plasticizers.

CWB Technology

CWB process uses a special heterogeneous catalyst to catalyze the cross-aldol reaction between formaldehyde and isobutyraldehyde to give intermediate hydroxypivaldehyde and then carry out catalytic hydrogenation on hydroxypivaldehyde to produce high purity neopentyl glycol.

Process Highlights:

  • Special and highly selective heterogeneous catalyst will be used to drive the aldol reaction between formaldehyde and isobutyraldehyde.
    • Side reactions including the Tischenko, Cannizzaro reactions are minimised
    • Higher per-pass yield than the conventional homogenous catalyst (e.g. metal hydroxides and trialkylamine) 
    • No tedious catalyst separation step will be involved after aldol reaction
  • A highly selective, low cost, Cr-free based hydrogenation catalyst will be used to give the best hydrogenation performance of hydroxypivaldehyde to neopentyl glycol, without sacrificing the reaction yield. 


  • More competitive formaldehyde and isobutyraldehyde consumption than other existing processes. 
  • High cost for chromium waste treatment will be eliminated
  • The entire technology is expected to be highly scaleable. Suitable for either small scale or industrial scale of production. 
  • Energy consumption through heat integration and optimised purification process will be reduced.

Safety and Environment:

  • Cr-free hydrogenation catalyst is used, no chromium wastes will be produced.
  • Overall side reactions are minimised and less valuable materials will be lost from purging. 

For more information regarding CWB NPG technology, please contact us at This email address is being protected from spambots. You need JavaScript enabled to view it..